Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Trimetazidine Dihydrochloride

Form: Tablet 35mg

Indication

Ischaemic heart disease, Angina pectoris, Coronary heart disease

Administration

Should be taken with food.

Adult Dose

Oral Angina pectoris Adult: 40-60 mg daily in 2-3 divided doses. Modified-release tab: 35 mg bid.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Contraindicated. 30-60 20 mg bid. Modified-release: 35 mg once daily.

Contraindication

Hypersensitivity to Trimetazidine Dihydrochloride.

Mode of Action

Trimetazidine is a cellular acting anti-ischaemic agent. It has 3 main properties by which it acts as a cytoprotective agent. It inhibits the anaerobic glycolysis and fatty acid metabolism, thus allowing only aerobic glycolysis. This action helps to restore the energy balance in the cell. It inhibits acidosis and free radical accumulation in the cell. All these action help the cell to restore the normal ionic and metabolic balance.

Introduction

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Uses of __NAME__

{'list': ['Angina (heart-related chest pain)']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Constipation', 'Dizziness', 'Headache', 'Nausea', 'Vomiting', 'Weakness']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is an anti-anginal medication. It decreases the oxygen requirement of the heart by shifting its metabolism from fats to glucose. As a result, the heart works more efficiently.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

__NAME__ may cause excessive drowsiness with alcohol.

Safety Advice

Information regarding the use of __NAME__ during pregnancy is not available. Please consult your doctor.

Safety Advice

Information regarding the use of __NAME__ during breastfeeding is not available. Please consult your doctor.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not recommended in patients with severe kidney disease.

Safety Advice

There is limited information available on the use of __NAME__ in patients with liver disease. Please consult your doctor.