Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Pazopanib Hydrochloride

Form: Tablet 200mg

Indication

Renal cell carcinoma, soft tissue sarcoma

Administration

Should be taken on an empty stomach: Take at least 1 hr before or 2 hr after meals. Swallow whole, do not break/crush.

Adult Dose

Advanced Renal Cell Carcinoma 800 mg PO qDay on empty stomach Soft Tissue Sarcomas 800 mg PO qDay on empty stomach Hepatic Impairment Billirubin <1.5 x ULN or ALT >ULN: No dosage adjustment required Billirubin >1.5-3 x ULN: Decreased dose to 200 mg PO qDay Billirubin >3 x ULN: Not recommended

Child Dose

Safety and efficacy not established; not indicated for use in pediatric patients

Renal Dose

Renal impairment: No dosage adjustment required

Contraindication

Hypersensitivity.

Introduction

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Uses of __NAME__

{'list': ['Kidney cancer', 'Soft tissue sarcoma']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Headache', 'Nausea', 'Vomiting', 'Musculoskeletal (bone, muscle or joint) pain', 'Fatigue', 'Change in color of hair', 'Diarrhea', 'High blood pressure', 'Decreased appetite', 'Weight loss', 'Taste change', 'Abnormal skin pigmentation', 'Hair discoloration', 'Tumor pain', 'Breathlessness']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ is to be taken empty stomach.

How __NAME__ works

__NAME__ is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (tyrosine kinase) that are responsible for the proliferation of the cancerous cells. It also restricts the growth of new blood vessels within the tumor. This is how it works against cancer.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ is safe to use in patients with kidney disease. No dose adjustment of __NAME__ is recommended.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not advised in patients with moderate to severe liver disease.