Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Mirabegron

Form: Tablet 50mg

Indication

Overactive bladder, with symptoms of urge urinary incontinence, urgency, and urinary frequency

Administration

May be taken with or without food: Swallow whole, do not chew/divide/crush.

Adult Dose

Overactive Bladder Indicated for overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency 25 mg PO qDay 25 mg dose is typically effective within 8 weeks May increase to 50 mg PO qDay based on individual efficacy and tolerability Hepatic impairment Moderate (Child-Pugh B): Not to exceed 25 mg/day Severe (Child Pugh C): Not recommended

Renal Dose

Renal impairment Severe (CrCl 15-29 mL/min): Not to exceed 25 mg/day ESRD: Not recommended

Contraindication

Hypersensitivity. Severe uncontrolled HTN.

Mode of Action

Beta-3 adrenergic receptor agonist which causes relaxation of the detrusor smooth muscle of the urinary bladder and increases bladder capacity.

Introduction

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Uses of __NAME__

{'list': ['Overactive bladder (OAB) symptoms']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Constipation', 'Headache', 'High blood pressure', 'Nasal inflammation', 'Urinary tract infection']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is a beta 3-receptor agonist. It works by activating the receptor in the bladder, causing the bladder muscles to relax. It prevents frequent, urgent or uncontrolled urination.

Safety Advice

Caution is advised when consuming alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ does not usually affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with severe kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not recommended in patients with severe liver disease.