Pack size: Box of 10 Tablets  |  Price is for the whole Box

Generic: Sulfasalazine

Form: Tablet 500mg

Indication

Inflammatory bowel disease, Rheumatoid arthritis

Administration

Should be taken with food. Take after meals. Ensure adequate fluid intake.

Adult Dose

Oral Inflammatory bowel disease Adult: Initially, 1-2 g 4 times daily until remission occurs. Maintenance: 2 g/day in divided doses. Rheumatoid arthritis Adult: As enteric-coated tablet: Initially, 500 mg daily for the 1st wk increased by 500 mg every wk. Max: 3 g daily in 2-4 divided doses. Rectal Inflammatory bowel disease Adult: As suppository: 0.5-1 g in the morning and night, either alone or as an adjunct to oral treatment. Hepatic impairment: Avoid use.

Child Dose

Oral Inflammatory bowel disease Child: >2 yr: 40-60 mg/kg/day in divided doses. Maintenance: 20-30 mg/kg/day in divided doses. Rheumatoid arthritis Child: For polyarticular juvenile rheumatoid arthritis: >6 yr: As enteric-coated tablet: 30-50 mg/kg/day in 2 divided doses. Begin treatment with 1/4 to 2/3 of expected maintenance dose and increase wkly to reach maintenance dose in 1 mth. Max: 2 g daily. Rectal Inflammatory bowel disease Child: As suppository (may be given as divided doses): 5-8 yr: 500 mg bid; 8-12 yr: 500 mg in the morning and 1 g at night; 12-18 yr: 1 g bid.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation 10-30ml/min Admin twice daily. <10ml/min Admin once daily.

Contraindication

Hypersensitivity to sulphonamides or salicylates, porphyria, <2 yr of age, intestinal or urinary obstruction, blood dycrasias, history of leucopenia with gold therapy.

Introduction

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Uses of __NAME__

{'list': ['Rheumatoid arthritis', 'Ulcerative colitis', 'Crohn’s disease', 'Ankylosing spondylitis']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Diarrhea', 'Gastrointestinal discomfort', 'Headache', 'Loss of appetite', 'Nausea', 'Oligospermia (low sperm count)', 'Vomiting', 'Weight loss']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ is to be taken with food.

How __NAME__ works

__NAME__ is a Disease Modifying Anti-Rheumatoid Drug (DMARD). It works by suppressing the overactivity of the immune system in autoimmune diseases and blocks the chemical messengers that cause inflammation (swelling).

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ does not usually affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Regular monitoring of kidney function tests is advisable while you are taking this medicine.

Safety Advice

__NAME__ is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.