Pack size: 1 4ml Bottle  |  Price is for the whole 4ml Bottle

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Pembrolizumab

Form: Injection 100mg/4ml

Indication

Metastatic melanoma, Unresectable melanoma, Locally advanced non-small cell lung carcinoma, Metastatic non-small cell lung carcinoma, Metastatic non-small cell lung carcinoma, Gastro-oesophageal junction adenocarcinoma, Locally advanced urothelial carcinoma, Metastatic gastric cancer, Metastatic microsatellite instability-high cancer, Metastatic squamous cell carcinoma of the head and neck, Metastatic urothelial carcinoma, Recurrent locally advanced gastric cancer, Recurrent squamous cell carcinoma of the head and neck, Refractory classical Hodgkin lymphoma, Relapsed classical Hodgkin lymphoma, Unresectable microsatellite instability-high cancer.

Administration

$49

Adult Dose

$4a

Mode of Action

Pembrolizumab is a humanised immunoglobulin G4 monoclonal antibody which binds to the cell surface receptor programmed death-1 (PD-1), a negative immunoregulatory protein, and prevents it from interacting with ligands PD-L1 and PD-L2. Blockade of the PD-1 pathway results in the reactivation of T-lymphocytes and induction of immune response to tumour cells.

Precaution

Patient with autoimmune disorders. Patients who received allogeneic haematopoietic stem cell transplant (HSCT) or solid organ transplant. Not indicated for multiple myeloma. Pregnancy and lactation. Lactation Unknown if distributed in human breast milk No studies conducted to assess impact of pembrolizumab on milk production or its presence in breast milk Instruct women to discontinue nursing during treatment and for 4 months after final dose

Side Effect

$4b

Introduction

$4c

Uses of __NAME__

{'list': ['Melanoma', 'Non-small cell lung cancer', 'Head and neck cancer', 'Cervical cancer']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Rash', 'Fatigue', 'Fever', 'Musculoskeletal (bone, muscle or joint) pain', 'Stomach pain', 'Nausea', 'Itching', 'Constipation', 'Indigestion', 'Diarrhea', 'Decreased appetite', 'Cough']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is an anti-cancer medication. It works in certain cancer by working with immune system thereby activating T-cell mediated immune responses against tumor cells.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

It is not known whether __NAME__ alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.