Pack size: Strip of 10 Capsules  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Nortriptyline

Form: Capsule 10mg

Indication

Depression, Nocturnal enuresis

Administration

May be taken with or without food.

Adult Dose

Oral Depression Adult: 75-100 mg/day in 3 or 4 divided doses. Max: 150 mg/day in severe depression. Elderly: 30-50 mg/day in divided doses. Hepatic impairment: Administer lower dose and titrate at a slower rate

Child Dose

Oral Depression Child: Adolescent: 30-50 mg/day in divided doses. Nocturnal enuresis Child: 6-7 yr (20-25 kg): 10 mg; 8-11 yr (25-35kg): 10-20 mg; >11 yr (35-54 kg): 25-35 mg. All doses are given 30 minutes before bedtime and treatment should continue for not >3 mth.

Contraindication

Mania, recent MI, arrhythmias (particularly heart block); severe liver disease; children <6 yr.

Mode of Action

Nortriptyline, a dibenzocycloheptadiene tricyclic antidepressant, is the primary active metabolite of amitriptyline. It increases synaptic concentration of serotonin and/or norepinephrine in the CNS by blocking the neuronal reuptake of norepinephrine and serotonin.

Introduction

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Uses of __NAME__

{'list': ['Depression', 'Bed-wetting']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Increased heart rate', 'Weight gain', 'Difficulty in urination', 'Orthostatic hypotension (sudden lowering of blood pressure on standing)', 'Dryness in mouth', 'Constipation']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

__NAME__ may cause excessive drowsiness with alcohol.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. As __NAME__ may affect your alertness which may affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of __NAME__ is not recommended in patients with severe liver disease.