Mitomycin

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৳51.25

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৳51.25

Overview
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Detail Description

Pack size: 1 2ml vial | Price is for the whole 2ml vial

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Crystalline Mitomycin-C

Form: Injection 2mg

Indication

Diabetic foot infections, Chronic lymphatic leukaemia, Chronic myelogenous leukaemia, Gastric carcinoma, Colorectal carcinoma, Lung carcinoma, Pancreatic carcinoma, Carcinoma Cervix, Endometrium carcinoma, Carcinoma Breast, Bladder carcinoma, Head & neck carcinoma.

Administration

IV Preparation Reconstitute with SWI to a concentration of 0.5 mg/mL IV Administration Administer slow IV push by central line only Flush with 5-10 mL of IV solution before & after drug administration

Adult Dose

Adult: IV Solid tumours Suggested regimen: Initial: 10-20 mg/m2; may repeat 6-8 wkly depending on blood count. Do not repeat if leucocyte and platelet counts are below acceptable levels. Do not re-administer if the nadir of the leucocyte count is <2,000 cells/mm3. Intravesical Superficial bladder tumours Instill 10-40 mg 1-3 times/wk for a total of 20 doses. Prevention of recurrent bladder tumours Instill 20 mg 2 wkly or 40 mg 1-3-mthly.

Child Dose

Safety and efficacy not established

Renal Dose

Renal Impairment Serum creatinine >1.7 mg/dL: Avoid use CrCl <10 mL/min: Decrease dose by 25% CAPD: Decrease dose by 25%

Contraindication

Thrombocytopenia, coagulation disorders, increase in bleeding tendency due to other causes. Renal impairment, potentially severe infections. Pregnancy and lactation.