Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Methylprednisolone Sodium Succinate

Form: Injection 500mg/vial

Indication

$4a

Administration

IV/IM Preparation Reconstitute for IM/IV injection with BWI containing 0.9% benzyl alcohol IV Administration Inject directly into vein or into tubing of running IV Injection: Administer over at least 1 minute Infusion: Further dilute reconstituted mixture with D5W, NS, D5/NS, or other compatible solution Push: Administer over 10-20 minutes

Adult Dose

Intramuscular Anti-inflammatory or immunosuppressive Adult: As methyprednisolone Na succinate: 10-80 mg once daily. Anti-inflammatory or immunosuppressive Adult: As methylprednisolone Na succinate: 10-500 mg daily. Doses <250 mg are given by inj over at least 5 min while doses >250 mg are given slowly over at least 30 min. Status asthmaticus Adult: As methylprednisolone Na succinate: 40 mg, repeated according to patient's response. Acute allograft rejection in organ transplant recipients Adult: As methylprednisolone Na succinate: 0.5-1 g daily; continue until the patient has stabilised, usually not beyond 48-72 hr.

Child Dose

Intramuscular Anti-inflammatory or immunosuppressive Child: As methylprednisolone Na succinate: 0.5-1.7 mg/kg daily or 5-25 mg/m2 daily in divided doses 6-12 hrly. "Pulse" therapy: 15-30 mg/kg/dose over >30 min given once daily for 3 days. Intravenous Anti-inflammatory or immunosuppressive Child: As methylprednisolone Na succinate: 0.5-1.7 mg/kg daily or 5-25 mg/m2 daily in divided doses 6-12 hrly. "Pulse" therapy: 15-30 mg/kg/dose over >30 min given once daily for 3 days. Status asthmaticus Child: As methylprednisolone Na succinate: 1-4 mg/kg daily for 1-3 days. Acute allograft rejection in organ transplant recipients Child: As methylprednisolone Na succinate: 10-20 mg/kg daily for up to 3 days. Max: 1,000 mg daily.

Contraindication

Systemic fungal infections and known hypersensitivity to components.

Mode of Action

Methylprednisolone is a synthetic corticosteroid with mainly glucocorticoid activity and minimal mineralocorticoid properties. It decreases inflammation by suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability.