Levofed

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Detail Description

Pack size: 1 Injection | Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Norepinephrine (Noradrenaline)

Form: Injection 2mg/2ml

Indication

Acute Hypotension, Cardiac Arrest, Sepsis & Septic Shock

Administration

IV Preparation & Administration Infuse using a solution of 4 mcg/ml in glucose 5%, or sodium chloride 0.9% and glucose 5% at a rate of 2-3 ml/minute. Adjust according to BP response. Average maintenance dose: 0.5-1 ml/minute (2-4 mcg/minute). Infuse via a central venous catheter or into a large vein.

Adult Dose

Intravenous Adult: Acute Hypotension, Cardiac Arrest Initial: 8-12 mcg/min IV infusion; titrate to effect Maintenance: 2-4 mcg/min IV infusion Sepsis & Septic Shock 0.01-3 mcg/kg/min IV infusion

Child Dose

Child: Acute Hypotension, Cardiac Arrest Initial: 0.05-0.1 mcg/kg/min IV infusion; titrate to effect Maximum: 1-2 mcg/kg/min Shock 0.05-0.1 mcg/kg/min IV infusion; titrate to effect; not to exceed 2 mcg/kg/min

Contraindication

Hypersensitivity. Hypertension. Pregnancy. Patients with peripheral or mesenteric vascular thrombosis unless necessary as a life-saving procedure. Concomitant use with some general anesthetics: Chloroform, trichloroethylene, cyclopropane, halothane

Mode of Action

Norepinephrine is a direct-acting sympathomimetic which stimulates alpha 1- and beta-adrenergic receptors. Its alpha-agonist effects cause vasoconstriction, thereby raising systolic and diastolic BP with reflex slowing of heart rate.