Generic: Moxifloxacin Hydrochloride Dexamethasone  |  Dosage Form: Ophthalmic Solution  |  Manufacturer: Gaco Pharmaceuticals Ltd.

Indications

Moxifloxacin & Dexamethasone eye drop is indicated in the treatment of eye infections caused by susceptible microorganisms and in the prevention of inflammation and bacterial infection that may occur after eye surgery.

Dosage & Administration

In the prevention of infection and post-surgical ocular inflammation: Instill 1 drop, 4 times a day, in the eye to be operated, from 1 day before surgery until 15 days after surgery.

In patients undergoing cataract surgery: The day of surgery instill the medication immediately after eye surgery.

In patients undergoing LASIK refractive surgery: On the day of surgery instill the medication at least 15 minutes after ocular surgery.

In eye infections caused by susceptible microorganisms: Instill 1 drop, 4 times a day, for up to 7 days.

Contraindications

Hypersensitivity to other quinolones and any components of the product. Patients with glaucoma and/or ocular disease causing thinning of the cornea or sclera; inflammation in the eye caused by virus, fungi or mycobacteria. Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella and many other viral diseases of the cornea, and conjunctiva. Mycobacterial infection of the eye. Fungal diseases of ocular structures.

Side Effects

Moxifloxacin: Conjunctivitis decreased visual acuity, dry eye, keratitis, Ocular discomfort, hyperemia, pain, Subconjunctival hemorrhage and tearing.

Dexamethasone: Visual acuity & field defects, cataract formation, secondary ocular infection following suppression of host response & perforation of the globe.

Precautions & Warnings

If an allergic reaction to Moxifloxacin occurs, discontinue use of the product and contact with doctor. Prolonged steroid use may result in ocular hypertension and/or glaucoma with damage to the optic nerve, defect in visual acuity and fields of vision, posterior subcapsular cataract formation, or increased hazard of developing secondary ocular infections. The intraocular pressure must be evaluated routinely. In those diseases causing thinning of the cornea or sclera (white part of the eye), perforations have been known to occur with use of topical corticosteroids. In acute purulent conditions of the eye, steroids may mask infection or enhance existing infection.

Overdose Effects

No information is available on overdosage with this product in humans.

Therapeutic Class

4-Quinolone preparations, Ophthalmic Steroid preparations

Storage Conditions

Store in a cool place, below 30°C, protected from light. Once the container is opened the contents must be used within 28 days and may be stored at room temperature up to 30°C. Discard after the 28 days. Keep out of reach of children.