Pack size: 1 Injection  |  Price is for the whole Injection

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Ketamine

Form: Injection 500mg/ml

Indication

Induction of anesthesia.

Administration

Reconstitution: 50 mg/mL and 100 mg/mL vials may be further diluted in 5% dextrose or 0.9% NaCl to prepare a maintenance infusion containing 1 mg/mL (or 2 mg/mL in patients w/ fluid restrictions).

Adult Dose

Intravenous Induction of anaesthesia Adult: 1-4.5 mg/kg via slow IV inj over 60 sec. A dose of 2 mg/kg produces surgical anaesthesia w/in 30 sec after inj lasting for 5-10 min. Increments of half to the full induction dose may be repeated as needed for maintenance of anesth. Alternatively, a total induction dose of 0.5-2 mg/kg via infusion, given at an appropriate rate, and maintained at a rate of 10-45 mcg/kg/min, adjusted according to response. Intramuscular Induction of anaesthesia Adult: 6.5-13 mg/kg. A dose of 10 mg/kg produces surgical anaesthesia w/in 3-4 min after inj lasting for 12-25 min. Increments of half to the full induction dose may be repeated as needed for maintenance of anesth. For diagnostic or other procedures not involving intense pain: 4 mg/kg as initial dose.

Contraindication

Hypertension, history of cerebrovascular accident. Eye injury, raised ocular and intracranial pressure. Psychotic disorders.

Mode of Action

Ketamine is a noncompetitive N-methyl-D-aspartate receptor antagonist that blocks glutamate. It has a direct action on the cortex and limbic system. It produces a cataleptic-like state wherein the patient is withdrawn from the surrounding environment.

Precaution

Minimise verbal and tactile stimulation during recovery period. Chronic alcoholic and alcohol-intoxicated patients. Preanaesthetic elevated CSF pressure. Dependence and tolerance may develop. May impair ability to drive or operate machinery. Monitor cardiac function in patients with hypertension or cardiac decompensation. Pregnancy and lactation.

Introduction

__NAME__ is a general anesthetic. It is used in major surgical procedures. It allows the procedures to be carried out without pain and distress. This injection is used in a hospital setting only. __NAME__ is used in general anesthesia. It causes loss of consciousness which is reversible. It is administered under the supervision of a healthcare professional. The most common side effects include rash, nausea or vomiting. Inform your doctor if you are pregnant or are suffering from severe heart disease or had a stroke recently or suffered serious head or brain injury. It is safe to use in breastfeeding mothers. Also, inform your doctor if you are on any medications or have any known allergy to this injection before the start of the procedure. Driving should not be done as __NAME__ may cause sleepiness and may impair your ability to think or react. It is also advised not to operate machinery because of these effects.

Uses of __NAME__

{'list': ['General Anaesthesia']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Rash', 'Erythema (skin redness)', 'Vomiting', 'Nausea', 'Agitation', 'Nightmare', 'Abnormal behavior', 'Double vision', 'Hallucination', 'Increased respiratory rate', 'High blood pressure', 'Confusion', 'Nystagmus (involuntary eye movement)', 'Muscle coordination impaired', 'Tonic-clonic seizures', 'Tachycardia']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is a general anaesthetic. It works by causing reversible loss of consciousness. This allows surgical procedures to be carried out without pain and distress.

Safety Advice

Caution is advised when consuming alcohol with __NAME__. Please consult your doctor.

Safety Advice

Information regarding the use of __NAME__ during pregnancy is not available. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ is safe to use in patients with kidney disease. No dose adjustment of __NAME__ is recommended. However, talk to your doctor if you have any underlying kidney disease.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.