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Detail Description

Pack size: 1 Capsule  |  Price is for the whole Capsule

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Deferiprone

Form: Capsule 250mg

Indication

Thalassaemia, Iron overload

Administration

May be taken with or without food.

Adult Dose

Transfusional Iron Overload Iron chelator indicated for treatment of transfusional iron overload caused by thalassemia syndromes when current chelation therapy is inadequate 25-33 mg/kg PO TID (ie, total daily dosage range 75-99 mg/kg/day) Round dose to nearest 250 mg

Contraindication

Agranulocytosis, pregnancy and lactation.

Mode of Action

Deferiprone is an orally effective iron-chelating agent. It is being used when desferrioxamine is unsuitable or contraindicated.

Precaution

Hepatic and renal impairment. Neutropenia, monitor neutrophil count wkly and discontinue treatment if neutropenia develops. Limited experience in children 6-10 yr. Lactation: Unknown whether distributed in breast milk; because of the potential for adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother

Introduction

__NAME__ is a medicine used in the treatment of chronic iron overload caused due to frequent blood transfusion. It helps removes excess iron and reduces the risk of it causing organ damage. __NAME__ should be taken in empty stomach. Take it regularly at a fixed time each day to get the maximum benefit of the medicine. Using of __NAME__ may cause common side effects such as nausea, headache, constipation, diarrhea and increased liver enzyme. If the side effects persist or worsen, inform your doctor.

Uses of __NAME__

{'list': ['Iron overload', 'Transfusion dependent thalassemia']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Fatigue', 'Headache', 'Nausea', 'Vomiting', 'Abdominal pain', 'Joint pain', 'Diarrhea']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

It is not known whether __NAME__ alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Safety Advice

There is limited information available on the use of __NAME__ in patients with kidney disease. Please consult your doctor. Regular monitoring of kidney function tests is advised in these patients while taking this medicine.

Safety Advice

There is limited information available on the use of __NAME__ in patients with liver disease. Please consult your doctor. Regular monitoring of liver function tests is advised in patients with liver disease while taking this medicine.

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