Pack size: 1 5ml Vial  |  Price is for the whole 5ml Vial

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Irinotecan Hydrochloride Trihydrate

Form: Injection 20mg/ml

Indication

Carcinoma of the colon or rectum

Administration

Reconstitution: Dilute in 5% dextrose injection (preferred) or 0.9% sodium chloride injection to a final concentration of 0.12-2.8 mg/ml.

Adult Dose

$49

Child Dose

Not recommended

Contraindication

Patients with a known hypersensitivity to the drug or its excipients.

Mode of Action

Irinotecan, a derivative of camptothecin, works by inhibiting the enzyme topoisomerase I thereby interfering with the coiling and uncoiling of DNA during replication and causing irreparable damage.

Introduction

$4a

Uses of __NAME__

{'list': ['Cancer of colon and rectum']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Fatigue', 'Nausea', 'Vomiting', 'Weakness', 'Hair loss', 'Fever', 'Anemia (low number of red blood cells)', 'Diarrhea', 'Decreased white blood cell count (neutrophils)', 'Decreased appetite', 'Mucosal inflammation']}

How to use __NAME__

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How __NAME__ works

__NAME__ is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, please consult your doctor.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor. Use of this medicine is not recommended for patients on dialysis.

Safety Advice

There is limited information available on the use of __NAME__ in patients with liver disease. Please consult your doctor.