Pack size: Box of 30 Capsules  |  Price is for the whole Box

Generic: Silymarin [Milk thistle]

Form: capsule 500mg

Indication

It is used for the treatment and prevention of- Liver disease, (non-alcoholic & alcoholic) , Liver cirrhosis, (non-alcoholic & alcoholic) Infectious hepatitis, Drug-induced hepatitis, Liver disease secondary to diabetes mellitus, Toxicity of narcotics, Fatty liver, Jaundice.

Administration

Administered only orally as advised by the physician.

Adult Dose

1 to 3 capsule(s) should be taken into 2 to 3 times daily or medication should be continued until the relief of symptoms according to the advice of physician.

Child Dose

It should not be given to children without advice of physician. Uses for below 12 years recommended after discussion with registered physician.

Renal Dose

It should be used with caution in patients with kidney disease. Dose adjustment of Silymarin [Milk thistle] may be needed. Please consult your doctor.

Contraindication

Contraindicated in patient with a known hypersensitivity to silymarin.

Introduction

__NAME__ is a flavonoid derived from Silybum marianum, a plant commonly known as milk thistle. __NAME__ exhibits hepatoprotective and regenerative properties and is one of the most widely used natural compounds for the treatment of hepatic diseases worldwide, due to its antioxidant, anti-inflammatory, and antifibrotic activities. __NAME__ also increases hepatic levels of glutathione by raising cysteine availability, while inhibiting its catabolism to taurine that may enhance the antioxidant defense in liver. __NAME__ was found to oppose oxidative stress, and to slow the progression of hepatic fibrosis in alcohol-fed baboons.

Uses of __NAME__

__NAME__ is used for the treatment of Jaundice,chronic inflammatory liver conditions, hepatic cirrhosis ,alcoholic liver damage.

Side effects of __NAME__

{'tag': 'Sometimes it cause', 'list': ['Mild digestive upset ', 'Allergic reactions']}

How to use __NAME__

Take __NAME__ in the dose and duration as advised by your doctor. Take __NAME__ orally with plenty of water. Do not chew, crush or break it.

How __NAME__ work

Different mechanisms of action of __NAME__ are as follow: Increasing the regenerative ability of the liver cells by enhancing the synthesis of DNA and RNA, as __NAME__ has a steroid structure; Altering the structure of the hepatocyte external membrane, that prevents entrance of the xenobiotics into the cell (poisoning with Amanita mushroom is a noteworthy example of such mechanism); Scavenging free radicals and increasing the cellular content of glutathione that leads to the inhibition of lipid peroxidation; Another mechanism of action of __NAME__ is modifying the transporters and receptors of cell membranes such as ABC transporters (P-gp), organic anion uptake transporter peptides (OATP), bile salt export pump, and TNF-α-dependent transporters.

What if you forget to take __NAME__

If you forget to take your__NAME__ , take them as soon as you remember. If it is almost time for your next dose, skip the missed dose and take it at the usual time. Avoid taking two doses at the same time.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ is not recommended for use during pregnancy. Controlled, long-term safety studies are lacking. Please consult your doctor.

Safety Advice

No experience is available about the use of __NAME__ .Long-term safety studies are lacking. Please consult your doctor.

Safety Advice

Limited research on the effects of __NAME__ on driving ability.

Safety Advice

It should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

It should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.