Pack size: Strip of 4 Capsules  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Amoxicillin + Clarithromycin + Lansoprazole Kit

Form: Capsule 30mg+500mg+1gm

Indication

Oral Eradication of H. pylori to reduce risk of duodenal ulcer recurrence Lansoprazole 30 mg, amoxicillin 1 g, clarithromycin 500 mg administered together PO twice daily (morning and evening) for 10 or 14 days Hepatic impairment: No dosage adjustment needed with hepatic impairment

Administration

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Adult Dose

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy, including amoxicillin. Although anaphylaxis is more frequent following parenteral therapy, it has occurred in patients on oral penicillins. These reactions are more likely to occur in individuals with a history of penicillin hypersensitivity and/or a history of sensitivity to multiple allergens. Lactation: Not recommended

Renal Dose

Lamsoprazole: Proton pump inhibitor; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells resulting in blocking acid secretion. Amoxicillin: Inhibits bacterial cell wall synthesis by binding to one or more penicillin binding proteins that in turn inhibit the final transpeptidation step of peptoglycan synthesis in cell wall biosynthesis. Clarithromycin: Inhibits protein synthesis by binding to 50S ribosomal subunit causing antibacterial activity.

Mode of Action

Combination therapy (lansoprazole, amoxicillin, clarithromycin) indicated for the treatment of patients with H. pylori infection and duodenal ulcer disease (active or 1-year history of a duodenal ulcer) to eradicate H. pylori To reduce development of drug-resistant bacteria and maintain efficacy of antibacterial drugs, use only to treat or prevent infections proven or strongly suspected to be caused by susceptible bacteria

Precaution

H. pylori infection, Peptic ulcer disease, Duodenal Ulcer

Introduction

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Uses of __NAME__

{'list': ['Peptic ulcer disease']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Nausea', 'Diarrhea', 'Stomach pain', 'Flatulence', 'Indigestion', 'Tiredness', 'Dizziness', 'Headache', 'Skin rash', 'Metallic taste', 'Dryness in mouth']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. __NAME__ is to be taken empty stomach.

How __NAME__ works

__NAME__ is a combination of 2 antibiotics (Tinidazole and Amoxycillin) and a proton pump inhibitor (PPI-Lansoprazole) which treat peptic ulcers caused by bacteria. Tinidazole reduces the amount of acid in the stomach and allows healing of ulcers. Amoxycillin kills bacteria and other microorganisms that cause infections by damaging their DNA. Lansoprazole works by preventing the formation of the bacterial protective covering that is essential for the survival of bacteria. Together, they treat your infection effectively.

Safety Advice

Consuming alcohol while taking __NAME__ may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. __NAME__ can have side effects and the symptoms (such as allergic reactions, dizziness and convulsions) may make you unfit to drive.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of this medicine is not recommended in patients with severe kidney disease.

Safety Advice

__NAME__ is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.