Pack size: 1 5ml drop  |  Price is for the whole 5ml drop

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Gentamicin + Hydrocortisone Acetate

Form: Ear Drop

Indication

Treatment of, chronic suppurative otitis media, otitis externa, and as prophylactic treatment of otitis externa following trauma, post-operative local use in surgery to infected mastoid cavities.

Adult Dose

Middle Ear Infection: Instill 2-4 drops in the affected ear three to four times a day and at night, or more frequently if required. Ear Canal Infection: Instill 2-4 drops in the affected ear three to four times a day and at night, or more frequently if required.

Contraindication

Contraindicated in patients with known or suspected perforation, or where there is a risk of perforation of the tympanic membrane. Known hypersensitivity to Hydrocortisone or Gentamicin or any other components of the product.

Mode of Action

Gentamicin is mixture of antibiotic substances produced by the growth of micromonospora purpurea. It is a bactericidal antibiotic which acts by inhibiting protein synthesis. It has greater antibacterial activity than streptomycin, neomycin or kanamycin. Gentamicin exerts a number of effects on cells of susceptible bacteria. It affects the integrity of the plasma membrane and the metabolism of RNA, but it's most important effect is inhibition of protein synthesis at the level of the 30s ribosomal subunit. Corticosteroids, such as hydrocortisone acetate, are used in pharmacological doses for their anti-inflammatory and immuno-suppressant glucocorticoid properties which suppress the clinical manifestation of disease in a wide range of disorders

Precaution

Long-term continuous therapy should be avoided. Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If an infection is not improved after one week, cultures and susceptibility tests should be performed to verify the identity of the organism and to determine what alternative therapy should be installed.

Side Effect

Ear discomfort, ear irritation may occur in rare cases. Gentamicin may cause irreversible partial or total deafness when given systemically or when applied topically to open wounds or damaged skin.

Introduction

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Uses of __NAME__

{'list': ['Bacterial infections']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Eye irritation', 'Eye discomfort']}

How to use __NAME__

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

How __NAME__ works

__NAME__ is a combination of two medicines: Gentamicin and Hydrocortisone. Gentamicin is an antibiotic. It stops bacterial growth in the eye by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Hydrocortisone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the eye red, swollen and itchy.

Safety Advice

No interaction found/established

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive.

Safety Advice

No interaction found/established

Safety Advice

No interaction found/established