Generic: Gabapentin | Dosage Form: Tablet | Manufacturer: Doctor TIMS Pharmaceuticals Ltd.
Indications
Gabapentin is indicated for-
- Neuropathic Pain.
- Adjunctive therapy in partial seizure and secondary generalized seizure.
Dosage & Administration
Neuropathic Pain: The treatment may be initiated as a single 300 mg dose on Day-1, than 300 mg twice on Day-2 and 300 mg thrice on Day-3. The dose can be subsequently be titrated up as needed for pain relief to a daily dose of 1800 mg (divided TID).
Epilepsy:
- Patients over 12 years of age: the effective dose of Gabapentin is 900 to 1800 mg/day given in three divided doses. The starting dose is 300 mg three times a day.
- Paediatric patients age 3-12 year: the starting dose should range from 10-15 mg/kg/day in 3 divided doses, and the effective dose reached by upward titration over a period of approximately three days.
Interaction
Antacids may reduce the bioavailability of Gabapentin by up to 20 %. Cimetidine may alter its reanal excretion. Gabapentin does not interact with other anti-epileptic drug or with oral contraceptive preparations.
Contraindications
Gabapentin is contraindicated in patients who have known hypersensitivity to the drug.
Side Effects
Fatigue, Dizziness, ataxia, weight gain, peripheral edema, dry mouth and somnolence may occur.
Precautions & Warnings
Patients should be instructed to take Gabapentin only as prescribed. While using Gabapentin patients should be instructed either not to drive a car or to operate other complex machinery until they have gained sufficient experiences about Gabapentin whether or not it affects their mental and/or motor performance adversely.
Therapeutic Class
Adjunct anti-epileptic drugs
Storage Conditions
Store below 25°C temperature. Protect from light and moisture. Keep all the medicines out of the reach of the children.