Eradra

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৳1,800.00

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৳1,800.00

Overview
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Detail Description

Pack size: 1 5ml | Price is for the whole 5ml

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Lifitegrast eye prep

Form: Drop 5%

Indication

Dry Eye Disease

Administration

Ophthalmic Administration Drops are in single-use containers; discard the single-use container immediately after using in each eye Remove contact lenses before instilling eye drops; may be reinserted 15 minutes following administration

Adult Dose

Eye drop Dry Eye Disease Indicated for treatment of the signs and symptoms of dry eye disease (DED) Instill 1 gtt q12hr into each eye

Child Dose

<17 years: Safety and efficacy not established

Mode of Action

The exact mechanism in dry eye disease is not known Binds to the integrin lymphocyte function-associated antigen-1 (LFA-1), a cell surface protein bound on leukocytes, and blocks the interactions of LFA-1 with its cognate ligand intercellular adhesion molecule-1 (ICAM-1) ICAM-1 may be overexpressed in corneal and conjunctival tissues in dry eye disease; LFA-1/ICAM-1 interaction can contribute to the formation of an immunological synapse resulting in T-cell activation and migration to target tissues In vitro studies demonstrated that lifitegrast may inhibit T-cell adhesion to ICAM-1 in a human T-cell line and may inhibit secretion of inflammatory cytokines in human peripheral blood mononuclear cells

Side Effect

>10% Instillation site irritation (5-25%) Dysgeusia (5-25%) Reduced visual acuity (5-25%) 1-10% Blurred vision (1-5%) Conjunctival hyperemia (1-5%) Eye irritation (1-5%) Headache (1-5%) Increased lacrimation (1-5%) Eye discharge (1-5%) Eye discomfort (1-5%) Eye pruritus (1-5%) Sinusitis (1-5%)