Pack size: 1 5gm Tube  |  Price is for the whole 5gm Tube

Generic: Lidocaine + Prilocaine topical

Form: cream 2.5%+2.5%

Indication

Local anaesthesia

Administration

Apply a thick layer to intact skin and cover with occlusive dressing. Gently squeeze cream out of the tube as a narrow strip that is 1.5 inches long and 0.2 inches wide; 1 strip corresponds to 1 g Perform local anesthetic infiltration immediately after removal of cream Male genital skin: Analgesia will increase up to 3 hours under occlusive dressing and persist 1-2 hours after cream removal Female genital skin: Occlusive dressing is not necessary but will keep cream in place

Adult Dose

Topical Dermal Procedures Minor dermatological procedures (e.g. IV cannulation or venipuncture): Cream: Apply 2.5 g over 20-25 cm² of skin surface area for at least 1 hr Painful dermatological procedures involving large areas (eg, split thickness skin graft harvesting) Cream: Apply 2 g/10 cm² of skin and allow to remain in contact with the skin for at least 2 hr Analgesia is achieved in 1 hr, reaches maximum in 2-3 hr, and persists 1-2 hr after removal Topical Anesthetic on Genital Mucous Membranes Superficial minor surgery on male genitalia and as pretreatment for infiltration anesthesia Cream: Apply 1 g/10 cm² of skin for 15 min Minor procedures on the female external genitalia (eg, condylomata acuminata) as well as for use as pretreatment for anesthetic infiltration Cream: Apply 5-10 g for 5-10 min

Child Dose

Local Anesthetic Procedures Cream Neonates (gestation age <37 weeks): Use not recommended <12 months: Do not use if receiving treatment with methemoglobinemia-inducing agents 0-3 months (or <5 kg): Do not exceed 1 g total dose/application area > 10 cm²/>1 hr application time 3-12 months (and >5 kg): Do not exceed 2 g total dose/application area > 20 cm²/>4 hr application time 1-6 years (and >10 kg): Do not exceed 10 g total dose/application area > 100 cm²/>4 hr application time 7-12 years (and >20 kg): Do not exceed 20 g total dose/application area > 200 cm²/>4 hr application time

Contraindication

Neonates with gestational age <37 wk. Infants <12 mth of age who are receiving treatment with methaemoglobin-inducing agents or children who are receiving medications associated with drug-induced methaemoglobinemia. Children with congenital or idiopathic methaemoglobinemia. Application on mucous membranes, broken or inflamed skin.

Mode of Action

Lidocaine and prilocaine are local anaesthetic agents of the amide type. Both work by stabilising the neuronal membranes and inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby giving rise to the anaesthetic action.

Introduction

$4c

Uses of __NAME__

{'list': ['Local anesthesia (Numb tissues in a specific area)']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Application site reactions (burning, irritation, itching and redness)', 'Rash']}

How to use __NAME__

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How __NAME__ works

__NAME__ is a combination of two medicines: Prilocaine and Lidocaine/Lignocaine. It works by blocking pain signals from the nerves of the affected area to t he brain. This decreases the sensation of pain.

Safety Advice

No interaction found/established

Safety Advice

__NAME__ is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

No interaction found/established

Safety Advice

No interaction found/established

Safety Advice

No interaction found/established