Pack size: 1 Tablet  |  Price is for the whole Tablet

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Methyldopa

Form: Tablet 250mg

Indication

Hypertension

Administration

May be taken with or without food.

Adult Dose

Oral Hypertension Adult: Monotherapy: Initially, 250 mg bid-tid for 2 days; adjust at intervals of at least 2 days according to response. Maintenance: 500-2,000 mg daily. Max: 3,000 mg daily. Combination therapy: Initial dose should not exceed 500 mg daily in divided doses. Elderly: Initially, 125 mg bid; gradually increase according to response. Max: 2,000 mg daily.

Child Dose

Oral Hypertension Child: <12 yr Initially, 10 mg/kg or 300 mg/m2 daily in 2-4 divided doses; adjust at intervals of at least 2 days according to response. Max: 65 mg/kg, 2,000 mg/m2 or 3,000 mg daily, whichever is least.

Renal Dose

Renal Impairment Adjust dosage frequency with renal impairment CrCl >50 mL/min: q8hr CrCl 10-50 mL/min: q8-12hr CrCl <10 mL/min: q12-24hr

Contraindication

Active liver disease (e.g. acute hepatitis, active cirrhosis) or depression. Concomitant use w/ MAOIs.

Introduction

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Uses of __NAME__

{'list': ['Hypertension (high blood pressure)']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Dizziness', 'Fatigue', 'Sleepiness', 'Dryness in mouth', 'Orthostatic hypotension (sudden lowering of blood pressure on standing)']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time. Avoid __NAME__ with high protein meals such as cottage cheese, Swiss cheese, protein powder, eggs and milk.

How __NAME__ works

__NAME__ is an alpha-2 agonist. It works by relaxing blood vessels which makes the heart more efficient at pumping blood around the body.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

Caution is advised when consuming alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Safety Advice

__NAME__ is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Regular blood pressure monitoring is recommended for dose adjustment.

Safety Advice

__NAME__ is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.