Pack size: 1 100ml bot  |  Price is for the whole 100ml bot

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Phenytoin

Form: Suspension 60mg/5ml

Indication

Epilepsy, Tonic-clonic status epilepticus

Administration

Should be taken with food. When administering to patients on nasogastric or other enteral feeds, do not administer feeds 2 hr before or after a dose. Be consistent throughout therapy in relation to feed times. Do not switch dosage forms/brands w/o prior consideration.

Adult Dose

Oral Epilepsy Adult: Initially, 3-4 mg/kg daily as single dose or in divided doses. Alternatively, 150-300 mg daily increased gradually to 600 mg daily if necessary. Maintenance: 200-500 mg daily.

Child Dose

Oral Control of Tonic-Clonic and Complex Partial Seizures Initial dosage Neonates: 5 mg/kg/day in 2 divided doses Child: 6 months to 16 years: 5 mg/kg/day in 2-3 divided doses Neonates (<28 days) Initial: 5-8 mg/kg/day PO divided q8-12hr Age-based maintenance dose 6 months-4 years: Usual range, 8-10 mg/kg/day PO divided two to three times daily 4-7 years: Usual range, 7.5-9 mg/kg/day PO divided two to three times daily 7-10 years: Usual range, 7-8 mg/kg/day IPO divided two to three times daily 10-16 years: Usual range, 6-7 mg/kg/day PO divided two to three times daily

Contraindication

Pregnancy.

Mode of Action

Phenytoin acts as an anticonvulsant by increasing efflux or decreasing influx of sodium ions across cell membranes in the motor cortex during generation of nerve impulses; thus stabilising neuronal membranes and decreasing seizure activity. It acts as an antiarrhythmic by extending the effective refractory period and suppressing ventricular pacemaker automaticity, shortening action potential in the heart.

Introduction

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Uses of __NAME__

{'list': ['Epilepsy/Seizures']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Rash', 'Headache', 'Dizziness', 'Vomiting', 'Nausea', 'Slurred speech', 'Vertigo', 'Confusion', 'Nervousness', 'Constipation', 'Tremor', 'Altered walking']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Please consult your doctor.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor.