Dezide (Strip of 10)

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৳50.00

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Detail Description

Pack size: Strip of 10 Tablets | Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Hydrochlorothiazide + Triamterene

Form: Tablet

Indication

Hypertension, Oedema

Administration

Should be taken with food. Take after meals.

Adult Dose

Hypertension 1-2 tablets/capsules (37.5-50 mg triamterene and 25 mg HCTZ) PO qDay 1 tablet (75 mg triamterene and 50 mg HCTZ) PO qDay Dosing considerations Monitor serum potassium Edema 1-2 tablets/capsules (37.5-50 mg triamterene and 25 mg HCTZ) PO qDay 1 tablet (75 mg triamterene and 50 mg HCTZ) PO qDay

Child Dose

Safety and efficacy not established

Contraindication

severe renal or hepatic impairment, preexisting or drug-induced hyperkalemia, patients at risk of respiratory or metabolic acidosis. Lactation.

Mode of Action

Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions. Triamterene is a potassium sparing diuretic which appears to act mainly on the distal renal tubules. It increases the excretion of Na and reduces the excretion of potassium. It adds to the natriuretic but reduces the kaliuretic effects of other diuretics. It is structurally similar to folate and has anti-folate activity.