Caripran 1.5 (Strip of 6)

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৳78.00

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Overview
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Detail Description

Pack size: Strip of 6 Capsules | Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Cariprazine

Form: capsule 1.5mg

Indication

Schizophrenia, Indicated for acute treatment of manic or mixed episodes associated with, bipolar disorder

Administration

Take orally with or without food

Adult Dose

Adults Schizophrenia Starting dose: 1.5 mg PO qDay Dose may be increased to 3 mg/day on Day 2 Depending upon clinical response and tolerability, further dose adjustments can be made in 1.5 to 3-mg increments Dosage range: 1.5-6 mg PO qDay Bipolar Disorder Indicated for acute treatment of manic or mixed episodes associated with bipolar I disorder Starting dose: 1.5 mg PO qDay Dose should be increased to 3 mg/day on Day 2 Depending on clinical response and tolerability, further dose adjustments can be made in 1.5 to 3-mg increments Dosage range: 3-6 mg PO qDay Hepatic impairment Mild-to-moderate (Child-Pugh score 5-9): No dosage adjustment required Severe (Child-Pugh score 10-15): Not recommended

Renal Dose

Renal impairment Mild-to-moderate (CrCl ?30 mL/min): No dosage adjustment required Severe (CrCl <30 mL/min): Not recommended; safety and efficacy has not been established

Contraindication

History of hypersensitivity to cariprazine

Mode of Action

Precise mechanism by which cariprazine works for schizophrenia or bipolar disorder is unknown Efficacy could be mediated through a combination of partial agonist activity at central dopamine (D2) and serotonin 5-HT1A receptors Forms 2 major metabolites, desmethyl cariprazine (DCAR) and didesmethyl cariprazine (DDCAR), that have in vitro receptor binding profiles similar to the parent drug