Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Mesalazine [5-aminosalicylic acid]

Form: Tablet 400mg

Indications

Treatment of mild to moderately active Ulcerative Colitis & Crohn’s Disease. Maintenance of remission of Ulcerative Colitis. Maintenance of remission of Crohn’s disease.

Administration

Swallow the tablets or capsules whole with a glass of water .The granules must not be chewed. The contents of the sachet should be emptied onto the tongue and washed down with some water.

Adult Dose

Ulcerative colitis- Adults: Active disease: Individual dosage, up to 4 gm once daily or divided into 2-4 doses. Maintenance treatment: Individual dosage. Recommended dosage, 2 gm once daily. Geriatrics: Patients who are 65 years or older, caution should be taken to closely monitor blood cell counts during Mesalamine therapy.

Child Dose

Pediatrics: The safety and efficacy in children below 6 years of age have not been established. There is only limited documentation for an effect in children (age 6-18 years). Children 6 years of age and older: Active disease: To be determined individually, starting with 30-50 mg/kg/day in divided doses. Maximum dose: 75 mg/kg/day in divided doses. The total dose should not exceed 4 g/day (maximum adult dose). Maintenance treatment: To be determined individually, starting with 15-30 mg/kg/day in divided doses. The total dose should not exceed 2 g/day (recommended adult dose). It is generally recommended that half the adult dose may be given to children up to a body weight of 40 kg; and the normal adult dose to those above 40 kg.

Renal Dose

Elderly patients are more likely to have decreased renal function, 5-aminosalicylic acid ( mesalazine) should be used with care.

Contraindication

Not recommended for patients who have a known hypersensitivity to salicylates or to any other component of the formulation.

Introduction

__NAME__ __FORM__is a anti-inflammatory agents used to treat inflammatory bowel disease and some forms of arthritis. __NAME__ __FORM__work by inhibiting the production of cyclo-oxygenase and prostaglandin, thromboxane synthetase, platelet activating factor synthetase, and interleukin-1 by macrophages so reduces the acute inflammatory response in inflammatory bowel disease.

Uses of __NAME__

__NAME__ __FORM__use as a treatment of inflammatory bowel disease (IBD) ,including ulcerative colitis and Crohn's disease.

Side effects of __NAME__

{'tag': '', 'list': ['Stomach upset', 'Nausea', ' Diarrhea', 'Headaches', 'Vomiting', 'Abdominal pain', 'Skin rash']}

How to use __NAME__

__NAME__ __FORM__ is usually take will depend on the severity of pataient condition and individual needs. It is important to take the medication exactly as prescribed by your doctor.Do not crush, chew, or break the tablet.__NAME__ __FORM__ may be taken on an empty or full stomach. However, taking it with to reduce the risk of stomach upset.

How __NAME__ works?

__NAME__ __FORM__ works by diminishes infammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon.

What if you forget to take __NAME__ ?

Take __NAME__ __FORM__as soon as you remember .If it is almost time for your next dose, skip the missed dose and take next dose at the regular time. Do not take two doses at the same time.

Safety Advice

Taking __NAME__ __FORM__ with alcohol can increase the risk of stomach upset and bleeding. Avoid alcohol while taking __NAME__ __FORM__

Safety Advice

__NAME__ __FORM__ has been shown to cross the placenta and may cause harm to the fetus. It should be given in pregnancy only if the potential benefit justifes the potential risk to the fetus.

Safety Advice

__NAME__ __FORM__has been shown to pass into breast milk that’s why should take caution to take it. Caution is advised when it is administered to a nursing mother.

Safety Advice

__NAME__ __FORM__is generally considered safe to take while driving. If there is any problem during driving, stop taking it.

Safety Advice

__NAME__ __FORM__ should be used with caution in patients who have known renal dysfunction or have a history of renal disease.

Safety Advice

Patients with liver disease should use __NAME__ __FORM__ with caution. The liver helps to break down __NAME__ __FORM__ and people with liver disease may have higher levels of 5-aminosalicylic acid (mesalazine) in their blood. This can increase the risk of side effects.