Pack size: 1 5ml bot  |  Price is for the whole 5ml bot

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Brinzolamide + Timolol eye prep

Form: Eye Drop 1%+0.5%

Indication

Treatment of elevated IOP in, open-angle glaucoma, ocular HTN

Adult Dose

1 drop into the affected eye(s) twice daily.

Contraindication

Bronchial asthma, severe COPD, sinus bradycardia, 2nd or 3rd degree AV block, overt cardiac failure, cardiogenic shock, severe allergic rhinitis, bronchial hyperreactivity, hyperchloraemic acidosis, severe renal impairment.

Mode of Action

Brinzolamide is a carbonic anhydrase inhibitor that decreases secretion of aqueous humor thus reducing intraocular pressure. Exact mechanism of ocular hypotensive effect is unclear, but it is thought to be related to reduction of aqueous humour formation. beta-blockade also causes lowering of BP.

Precaution

Control cardiac failure prior to therapy. History of severe cardiac & resp disease. Patients subject to hypoglycemia or labile insulin-dependent diabetes. May mask hyperthyroidism or worsen Prinzmetal's angina, severe peripheral & central circulatory disorders & hypotension. History of atopy or severe anaphylactic reaction to a variety of allergens. Avoid concomitant use of 2 local beta-adrenergic blockers or 2 local carbonic anhydrase inhibitors. Close monitoring of IOP in patients w/ pseudoexfoliative or pigmentary glaucoma. Narrow-angle glaucoma. Monitor patients w/ compromised corneas eg patients w/ DM or corneal dystrophies. Remove contact lenses prior to application; reinsert after 15 min. May impair ability to drive or operate machinery. Pregnancy. Childn <18 yr.

Side Effect

Dysgeusia, blurred vision, eye pain & irritation, foreign body sensation.

Introduction

$4a

Uses of __NAME__

{'list': ['Ocular hypertension', 'Glaucoma']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Itching', 'Irritation', 'Stinging sensation', 'Burning sensation in eye', 'Blurred vision', 'Eye redness', 'Taste change']}

How to use __NAME__

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

How __NAME__ works

__NAME__ is a combination of two medicines: Brinzolamide and Timolol. Brinzolamide is a carbonic anhydrase inhibitor while Timolol is a beta blocker. They work by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.

Safety Advice

No interaction found/established

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.

Safety Advice

No interaction found/established

Safety Advice

No interaction found/established