Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Anastrozole

Form: Tablet 1mg

Indication

Oral Advanced or locally advanced breast cancer, Adjuvant treatment in early breast cancer Adult: In postmenopausal women: 1 mg daily. Adjuvant treatment may be continued for up to 5 yr. Hepatic Impairment Mild-to-moderate impairment or stable hepatic cirrhosis: Dose adjustment not necessary Severe hepatic impairment: Not studied

Administration

Efficacy decreased by oestrogens. Plasma concentrations decreased by tamoxifen.

Adult Dose

Moderate or severe hepatic impairment, hyperlipidaemias. Laboratory test for menopause if status is doubtful. Bone mass density test should be conducted at the start of the therapy and at regular intervals thereafter. Lactation: Unknown whether drug is excreted in milk; not recommended given potential for serious adverse reactions in nursing infants

Renal Dose

Anastrozole prevents conversion of androstenedione to estrone and testosterone to oestradiol by inhibiting aromatase, thus leading to significantly reduced serum oestradiol concentrations.

Mode of Action

May be taken with or without food.

Precaution

Breast cancer, Ovulation induction

Introduction

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Uses of __NAME__

{'list': ['Breast cancer']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Headache', 'Musculoskeletal (bone, muscle or joint) pain', 'Nausea', 'Osteoporosis', 'Skin rash', 'Weakness']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is an aromatase inhibitor. It works by lowering the amount of estrogen (natural female hormone) produced in the body. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Safety Advice

It is not known whether it is safe to consume alcohol with __NAME__. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Safety Advice

__NAME__ is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Safety Advice

__NAME__ may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Safety Advice

__NAME__ should be used with caution in patients with severe kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Limited information is available on the use of __NAME__ in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Safety Advice

__NAME__ should be used with caution in patients with liver disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Limited information is available on the use of __NAME__ in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.