Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Amisulpride

Form: Tablet 100mg

Indication

Acute and chronic schizophrenic disorders, in which positive symptoms (such as delusions, hallucinations, thought disorders) and/or negative symptoms (such as blunted affect, emotional and social withdrawal) are prominent, including patients characterised by predominant negative symptoms.

Adult Dose

Adult Acute episodes, 400—800mg daily in two divided doses. Adjust according to response; max 1.2g daily. Mixed positive and negative symptoms, adjust dose to control positive symptoms. Predominant negative symptoms, 50—300mg once daily. Elderly: Dose reduction may be required. Hepatic Failure: Since the drug is weakly metabolised a dosage reduction should not be necessary.

Child Dose

Under 18 years, not recommended.

Renal Dose

Amisulpride is eliminated by the renal route. In renal insufficiency, the dose should be reduced to half in patients with creatinine clearance (CRCL) between 30-60 ml/min and to a third in patients with CRCL between 10-30 ml/min. As there is no experience in patients with severe renal impairment (CRCL < 10 ml/min) particular care is recommended in these patients

Contraindication

Prolactin-dependent tumours, phaeochromocytoma. Lactation.

Mode of Action

Amisulpride binds selectively with a high affinity to human dopaminergic D2/D3 receptor subtypes whereas it is devoid of affinity for D1, D4 and D5 receptor subtypes.

Introduction

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Uses of __NAME__

{'list': ['Schizophrenia']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Nausea', 'Vomiting', 'Dryness in mouth', 'Constipation', 'Weight gain', 'Decreased blood pressure', 'Dystonia (involuntary muscle contractions)', 'Akathisia (inability to stay still)', 'Parkinsonism', 'Increased prolactin level in blood']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ may be taken with or without food, but it is better to take it at a fixed time.

How __NAME__ works

__NAME__ is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Safety Advice

It is unsafe to consume alcohol with __NAME__.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. You may feel less alert, drowsy or sleepy while taking this medicine. This may affect your driving ability.

Safety Advice

__NAME__ should be used with caution in patients with kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Use of __NAME__ is not recommended in patients with severe kidney disease.

Safety Advice

__NAME__ is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.