Pack size: Strip of 10 Tablets  |  Price is for the whole Strip

⚠ Prescription required. This medicine may only be dispensed against a valid prescription.

Generic: Alendronic Acid (Alendronate)

Form: Tablet 10mg

Indication

Adult: PO Osteoporosis 10 mg/day or 70 mg once wkly. Prevention of postmenopausal osteoporosis 5 mg/day or 35 mg once wkly. Corticosteroid-induced osteoporosis 5 mg/day; up to 10 mg/day in women not on HRT treatment. Paget's disease of bone 40 mg/day for 6 mth. May repeat after an interval of 6 mth if needed.

Administration

Concomitant iron, calcium supplements and antacids hinder alendronate absorption. Concomitant aspirin or NSAIDs may increase the incidence of adverse GI effects.

Adult Dose

Upper GI disorders (discontinue if symptoms worsen); history of ulcers, active GI bleeding. Correct vitamin D and calcium deficiency before starting therapy. To be taken half an hr before breakfast and remain upright for at least 30 minutes after admin. Not recommended for use in patients with CrCl <35 ml/min. Lactation: Unknown whether drug is excreted in milk; use with caution.

Renal Dose

Alendronic acid reduces bone resorption by inhibiting the action of osteoclasts.

Mode of Action

Administration Take only in morning, not at bedtime or before arising Take tablet with full glass of water (6-8 oz) at least 30 minutes before first food or drink of day, in upright position Administer oral solution with at least 2 ounces of water Swallow with plain water only; mineral water, coffee, juice or other beverages severely reduces bioavailability Swallow tablet whole; do not suck or chew Do not lie down for 30 minutes after taking drug; sit or stand upright

Precaution

Osteopetrosis, postmenopausal osteoporosis, Paget's disease of bone.

Introduction

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Uses of __NAME__

{'list': ['Osteoporosis']}

Side effects of __NAME__

{'tag': 'Common', 'list': ['Diarrhea', 'Headache', 'Heartburn', 'Musculoskeletal (bone, muscle or joint) pain']}

How to use __NAME__

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. __NAME__ is to be taken empty stomach.

How __NAME__ works

__NAME__ is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

What if you forget to take __NAME__?

If you miss a dose of __NAME__, skip it and continue with your normal schedule. Do not double the dose.

Safety Advice

Consuming alcohol with __NAME__ does not cause any harmful side effects.

Safety Advice

__NAME__ may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Safety Advice

__NAME__ is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. If you are taking __NAME__ during breastfeeding, monitor baby's blood calcium levels during the first two months.

Safety Advice

__NAME__ may cause side effects which could affect your ability to drive. __NAME__ is not expected to have any effects but in rare cases, it may cause dizziness, severe muscle, joint and bone pain and eye pain or inflammation. This may affect your ability to drive.

Safety Advice

__NAME__ should be used with caution in patients with severe kidney disease. Dose adjustment of __NAME__ may be needed. Please consult your doctor. Dose adjustment is not recommended in patients with mild to moderate kidney disease.

Safety Advice

__NAME__ is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of __NAME__ may not be needed in these patients. Please consult your doctor.